Acoustic Stimulation Promotes DNA Fragmentation in the Guinea Pig Cochlea

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Acoustic stimulation promotes DNA fragmentation in the Guinea pig cochlea.

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The effect of sound stimulation on phosphoinositide turnover was investigated in the inner ear of the guinea pig. The perilymphatic spaces of the cochlea were perfused with [(32)P]orthophosphate ((32)P(i)) and labeled lipids analyzed in the tissues of the lateral wall of the cochlea (stria vascularis and spiral ligament) and the basilar membrane (organ of Corti). Consistent with previous result...

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Spatial overlap of combined electroacoustic stimulation determines the electrically evoked response in the guinea pig cochlea.

HYPOTHESIS Limiting spatial overlap between electrical stimulation (ES) and acoustical stimulation (AS) in the cochlea reduces the effects of AS on electrically evoked auditory nerve activity. BACKGROUND Some hybrid cochlear implant systems have a regular array, whereas others have short arrays that spatially segregate ES from AS. AS settings in hybrid implants may also affect electroacoustic...

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Immunocytochemical localization of glutamate immunoreactivity in the guinea pig cochlea.

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An M-like potassium current in the guinea pig cochlea.

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ژورنال

عنوان ژورنال: Journal of Nippon Medical School

سال: 2012

ISSN: 1345-4676,1347-3409

DOI: 10.1272/jnms.79.349